Rekombinanter Human IgG4 Isotyp-Kontrolle
In vivo Grade
IsoC, in vivo
IgG4
Recombinant Antibody
unconjugated
Produktnummer ABIN7211744
Kurzübersicht für Rekombinanter Human IgG4 Isotyp-Kontrolle (ABIN7211744)
Target
IgG4
Antikörpertyp
Recombinant Antibody
Applikation
Isotype Control (IsoC), In vivo Studies (in vivo)
Güteklasse
In vivo Grade
Isotyp
IgG4
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Reaktivität
- Human
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Wirt
- Human
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Expressionssystem
- Mammalian cells
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Verwendungszweck
- In Vivo Grade Recombinant Human IgG4 Fc Protein
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Produktmerkmale
- Human IgG4 Fc is the tail region of the immunoglobulin G4 (IgG4) that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. The ~230 amino acid fragment generally exists as a dimer, although under reducing conditions, it exists as a monomer. It is the basis of prolonged pharmacokinetics of antibodies and is commonly used as a fusion to extend half-life of fusion proteins. IgG4's hinge is shorter than that of IgG1, its flexibility is intermediate between IgG1 and IgG2 and some rotation may occur around the glycine residue in its hinge region.
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Aufreinigung
- Protein A or G affinity column
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Reinheit
- >95 % by SDS-PAGE under reducing conditions
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Sterilität
- Sterile filtered
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Endotoxin-Niveau
- < 1 EU per 1 mg of the protein by the LAL method
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4
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Lagerung
- 4°C,-20 °C
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Informationen zur Lagerung
- 1 month from date of receipt, 2 to 8°C as supplied. 3 months from date of receipt, -20°C to -70°C as supplied.
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Haltbarkeit
- 3 months
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- IgG4
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Substanzklasse
- Antibody
Target
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